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Last Updated: Feb 12, 2023
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Reasons Why IVF Cycle Is Cancelled

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Dr. Rita BakshiIVF Specialist • 41 Years Exp.MBBS, DGO, MD, Fellowship in Gynae Oncology
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In vitro fertilisation (IVF) is a precarious treatment, which is filled with hope and despair in equal measures. While you cannot wait to have a baby through IVF and you are terribly excited when the IVF cycle starts with some success, you still need to be prepared to face disappointment at any stage in the cycle.

There are certain reasons why an IVF cycle can be cancelled. Some of the reasons include:

  1. Ovarian cysts: As an important part of pre-treatment in IVF, a screening is done to check for ovarian cysts. If you do have a cyst in your ovary, the date for the commencement of IVF will be pushed back. Medicines will be prescribed to reduce the cysts in such a case.
  2. Poor stimulation responses: Usually, more than three follicles in the ovaries are needed to produce eggs. Fertility drugs are given to stimulate the growth of the follicles. But sometimes, there is poor response to the drugs and the needed number of follicles might not grow. In this case, either the IVF cycle is cancelled or different medication is used.
  3. Hyperstimulation: On one hand, there is poor or under active response to fertility drugs and then there is hyperstimulation; which is an overactive response to the drugs. This leads to excessive growth of follicles, which causes ovarian hyperstimulation syndrome (OHS). The cycle is cancelled as OHS might cause serious problems in the womb.
  4. Decline in estradiol levels: The ovaries produce a type of estrogen called estradiol. When egg follicles grow, estradiol is secreted, which triggers the rest of the cycle. If the levels of estradiol drop, follicular development is hindered. In this case, the IVF cycle will be cancelled.
  5. Poor egg retrieval: Usually, an ultrasound is done to check the amount of mature eggs before the retrieval. Sometimes, fewer eggs are collected than what were expected. If egg retrieval is poor, the cycle will not move any further.
  6. Poor fertilization: Poor sperm or egg equality might hamper the process of fertilization, which will thus impact the development of the embryo. If the embryo does not form at all, the cycle will obviously be cancelled.
  7. Illness: If you or your partner has high fever or fall ill anytime during the process, the IVF cycle may be abandoned.

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